Lucy DeVito made her Broadway debut in 2023 in I Need That at the Roundabout Theatre, a play written by American playwright Theresa Rebeck, specifically for Lucy and her father Danny DeVito. Other theater and off-Broadway work includes: Hot Mess, Love Loss and What I Wore, Bump, How My Grandparents Fell in Love, Lucy, Steel Magnolias, The Electric Baby, In Quietness, Miracle at Naples, The Diary of Anne Frank. Film work includes: The Secret Art of Human Flight, The List, Blonde, Cubby, The Comedian, Leaves of Grass, Sleepwalk With Me, Can You Ever Forgive Me, and Curmudgeons. Television work includes: The Marvelous Mrs. Maisel, Deadbeat, Shameless, Girls, and Melissa and Joey. She voiced the lead character in FXX’s Little Demon, and served as an executive producer. DeVito is co-president of Jersey Films 2nd Ave.